How can cannabis help increase appetite?

• The endocannabinoid system plays a role in regulating appetite, among other functions. By interacting with the endocannabinoid system, cannabinoids can help stimulate appetite.
• Ghrelin production: THC, the main psychoactive compound in cannabis, has been found to increase the production of ghrelin, a hormone that stimulates appetite. Ghrelin, is also know as the “hunger hormone”.
• Taste and smell enhancement: Cannabis can enhance the taste and smell of food, making it more appealing and potentially increasing appetite.
• Nausea relief: Cannabis has been found to have anti-nausea properties, which can help individuals who are experiencing nausea or loss of appetite due to medical conditions or treatments.

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How can cannabis help to decrease appetite?

While cannabis is often associated with increasing appetite, there is some evidence to suggest that it can also help decrease appetite through a few mechanisms:

1. CBD: Cannabis contains two primary compounds, which can have different effects on appetite. While THC has been found to increase appetite, CBD has been found to have appetite-suppressing effects. Therefore, cannabis strains with higher CBD content may be more effective at reducing appetite.
2. THCV (tetrahydrocannabivarin) is a minor cannabinoid found in some strains of cannabis that has been found to potentially help decrease appetite through a few mechanisms:
   • Activation of CB1 and CB2 receptors: THCV has been found to interact with both CB1 and CB2 receptors in the body, which are involved in regulating appetite and metabolism. By modulating these receptors, THCV may help reduce appetite and promote weight loss.
   • Regulation of blood sugar: THCV has been found to potentially help regulate blood sugar levels, which can in turn affect appetite. By stabilizing blood sugar, THCV may help reduce cravings and promote feelings of fullness.
   • Activation of CB1 and CB2 receptors: THCV has been found to interact with both CB1 and CB2 receptors in the body, which are involved in regulating appetite and metabolism. By modulating these receptors, THCV may help reduce appetite and promote weight loss.
   • Regulation of blood sugar: THCV has been found to potentially help regulate blood sugar levels, which can in turn affect appetite. By stabilizing blood sugar, THCV may help reduce cravings and promote feelings of fullness.

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Promotion of energy expenditure:

THCV has been found to potentially promote energy expenditure, which can help burn calories and aid in weight loss.

Regulation of glucose metabolism:

• Cannabis has been found to have effects on glucose metabolism, which can in turn affect appetite. By regulating glucose levels, cannabis may help reduce cravings and promote feelings of fullness.

Anxiety and stress relief:

• Chronic stress and anxiety can lead to overeating and weight gain, and cannabis has been found to have anxiolytic (anxiety-reducing) and stress-reducing properties. By reducing anxiety and stress, cannabis may help individuals avoid emotional eating and reduce overall caloric intake.

It is important to note THCV is not psychoactive, unlike THC.